AAV-mo.1	AAV-ra.1	AAV-1	AAV-2	AAV-hu.2	AAV-3a	AAV-4	AAV-5	AAV-7	AAV-8	AAV-9	Avian	Snake
% Amino acid identity
AAV-mo.1	100	58	56	56	56	55	51	53	56	56	56	50	50
AAV-ra.1	58	100	52	52	52	50	46	58	52	52	52	47	48
% Nucleotide identity
AAV-mo.1	100	60	59	58	59	58	56	58	58	59	58	61	53
AAV-ra.1	60	100	60	59	59	58	56	68	60	61	60	60	51

Amino acid sequences of capsids that represent each clade of AAV are shown. AAV-1 (GenBank accession NC_002077) represents clade A. AAV-2 (GenBank accession AF043303) represents clade B. AAV-hu.2 (GenBank accession AY530585) is a hybrid between AAV-2 and AAV-3 capsid sequences and represents clade C. AAV-7 (GenBank accession AF513851) represents clade D. AAV-8 (GenBank accession AF513852) represents clade E. AAV-9 (GenBank accession AX753250) represents clade F. AAVs that have not been assigned clade designations but represent distinct lineages based on taxonomic analysis include AAV-3a (GenBank accession NC_001729), AAV-4 (GenBank accession NC_001829), AAV-5 (GenBank accession AF085716), avian AAV (GenBank accession AY629582), and snake AAV (GenBank accession AY349010). Capsid amino acid sequences within a clade are at least 85% identical to each other.