Pre-made recombinant lentivirus; LV-hSyn-hM4D(Gi)-mCherry; Syn-hM4D(Gi)-mCherry Lentivirus
Product Category: Pre-made
recombinant lentivirus; LV-hSyn-hM4D(Gi)-mCherry; Syn-hM4D(Gi)-mCherry
Lentivirus
Description: LV-hSyn-hM4D(Gi)-mCherry is
a pre-made lentivirus which expresses Gi-coupled hM4D DREADD fused with mCherry
under the control of human synapsin promoter. The transgene was modified form of
human Gi-coupled M4 muscarinic receptor, belonging to a class of chemogenetic
receptors called designer receptors exclusively activated by designer drugs (DREADD)
which allows engagement
of the Gi signaling pathway in the presence of the synthetic ligand clozapine-N-oxide
(CNO), leading to intracellular calcium ion release and
inhibit neuronal
excitation. Ready
to use format.
Titer: >
1x109 TU/mL
Selection Antibiotic: Puromycin
Purity*: In
vivo grade and OK for both in vitro tissue culture infection and in vivo
injection
Size: 2
x 25 µL (Std Pack)
Storage Buffer: PBS
Infection Protocol: 
Transfer Vector Map:
-mCherry.png)
* Concentrated
via PEG precipitation followed by ultra-centrifugation
at 25000 rpm