Pre-made recombinant AAV; AAV-CAG-GFP-3xmiR122; AAV-CBA-GFP-3xmiR122; AAV(BI30)-CAG-GFP-3xmiR122; AAV(BI30)-CBA-GFP-3xmiR122
Product
Category: Pre-made
recombinant AAV; AAV-CAG-GFP-3xmiR122; AAV-CBA-GFP-3xmiR122;
AAV(BI30)-CAG-GFP-3xmiR122;
AAV(BI30)-CBA-GFP-3xmiR122
Description: AAV(BI30)-CAG-GFP-3xmiR122
is a pre-packaged rAAV in serotype BI30
(a
capsid with tropism for CNS endothelial cells) which over-expresses EGFP
with miR122 target sequence repeats to reduce transgene expression in
hepatocytes
under
the CAG (also known as
CBA) promoter. The CAG promoter is a combination of the cytomegalovirus (CMV) early
enhancer element and chicken beta-actin promoter for high levels of gene
expression in mammalian expression vectors. Compared
with rAAV serotype 9, rAAV in serotype BI30 is able to penetrate brain-blood
barrier (BBB) and infect CNS via tail vein I.V. with 50 times better
transduction efficiency. Ready to use format.
Titer: >
1x1013 VG/mL
Size: 30 µL
(Std Pack)
Storage Buffer: Sterile
PBS
Infection Protocol: 
Vector Map:
