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rAAV Production Serivce

Adeno-associated virus (AAV) Custom Production Service:

Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell.

With our proprietary genetically engineered AAV·HT™ packaging cell, we are offering custom rAAV vector production services (conventional single stranded or double-stranded also known as self-complementary**) listed as follows to fit your different research needs.

Catalog #	Service Items	*Final Deliverable (VG)**	rAAV Purity	Lead Time
SL100801	rAAV Production, Full Service, Large Scale	>1E+13 VG (1.0 mL at >1E+13 VG/mL)	In Vivo Grade	3~4 weeks
SL100861	rAAV Production, Full Service, Medium Scale	>2E+12 VG (0.2 mL at >1E+13 VG/mL)	In Vivo Grade	3~4 weeks
SL100865	rAAV Production, Full Service, Pilot Scale	>1E+12 VG (0.1 mL at >1E+13 VG/mL)	In Vivo Grade	3~4 weeks
SL100862	rAAV Packaging Service, Large Scale	>1E+13 VG (1.0 mL at >1E+13 VG/mL)	In Vivo Grade	1~2 weeks
SL100863	rAAV Packaging Service, Medium Scale	>2E+12 VG (0.2 mL at >1E+13 VG/mL)	In Vivo Grade	1~2 weeks
SL100864	rAAV Packaging Service, Pilot Scale	>1E+12 VG (0.1 mL at >1E+13 VG/mL)	In Vivo Grade	1~2 weeks

Large AAV cis vector collection offers tremendous flexibility for choosing a specific promoter and reporter.

Single promoter rAAV cis vector		Dual promoter rAAV cis vector
Promoterless CMV CAG H1 U6 Synapsin UBC EF1α ALB(1.4) ApoE/AAT1 CaMKII ELA1 Enh358MCK cTNT GFAP MBP SST TBG αMHC hRPE mIP1 tMCK		Promoterless CMV CAG H1 U6 Synapsin UBC EF1α ALB(1.4) ApoE/AAT1 CaMKII ELA1 Enh358MCK cTNT GFAP MBP SST TBG αMHC hRPE mIP1 tMCK	CMV CAG H1 U6 Synapsin UBC EF1α CaMKII cTNT GFAP	eGFP RFP mRFP mCherry tdTOMATO TurboGFP eYFP Venus Luc LacZ

With our proprietary genetically engineered AAV·HT™ packaging cell and a modified rAAV cis vector, the rAAV yield is easy to reach super high level--------total 1E+15 VG. For super high level rAAV production up to 1E+15 VG total , please contact us to request a quote.

* Final viral yield may depend on the nature of transgene.
** Some terms may apply for custom double stranded or self-complementary rAAV production.

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