The following siRNA sequences were efficacious in knocking down dystonin-a1 and dystonin-a2 expression, respectively:

Group A:
Sense: 5’-ACAUGUACGUGGAGGAGCA-3’ / Antisense: 5’-UGCUCCUCCACGUACAUGU-3’;
Sense: 5’-CAAGCAUGAGAGAUCCAAA-3’ / Antisense: 5’-UUUGGAUCUCUCAUGCUUG-3’;

Group B:
Sense: 5’-CAAGCAUGAGAGAUCCAAA-3’ / Antisense: 5’-UUUGGAUCUCUCAUGCUUG-3’;
Sense: 5’-CUUCCUCUUGUUGCUCCUG-3’ / Antisense: 5’-CAGGAGCAACAAGAGGAAG-3’