Product Category:
Pre-made rAAV Empty Capsid | AAV Empty Capsid | AAV5 Empty Capsid
Description:
The AAV5 Empty Capsid is a pre-made recombinant
AAV (rAAV) capsid in serotype 5. The
production of AAV empty capsids involves the assembly of viral capsid
proteins without incorporating a DNA genome inside. The process requires
precise manipulation of AAV vector production systems to ensure efficient
capsid assembly while limiting genome packaging. Manufactured using a
proprietary AAV packaging protocol and purified through two rounds of CsCl
isopycnic ultracentrifugation, this product ensures 100% empty capsid
content, as verified by Refeyn Mass Photometer analysis.
Used as controls in research, manufacturing processes, immunogenicity
studies or quality control during therapeutic AAV production.
Figure 1. The AAV5 empty capsid was diluted 100- to
1000-fold before loading into the cartridge for mass photometry analysis.
Sterile PBS was used both as the diluent with the Thyroglobulin
(660 kDa) for mass calibration.
Titer: >
1x1013 Capsid/mL
Size:
30 µL (Std
Pack)
Storage Buffer: Sterile
PBS supplemented with 0.005% Pluronic F-68
