Adeno-associated virus (AAV) Custom Production Service:
Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell.
With our proprietary genetically engineered AAV·HT™ packaging cell, we are offering custom rAAV vector production services (conventional single stranded or double-stranded also known as self-complementary**) listed as follows to fit your different research needs.
Catalog # | Service Items | Final Deliverable (VG*) | rAAV Purity | Lead Time |
SL100801 | rAAV Production, Full Service, Large Scale | 1.0 mL at >1E+13 VG/mL | In Vivo Grade | 3~4 weeks |
SL100861 | rAAV Production, Full Service, Medium Scale | 0.2 mL at >1E+13 VG/mL | In Vivo Grade | 3~4 weeks |
SL100865 | rAAV Production, Full Service, Pilot Scale | 0.1 mL at >1E+13 VG/mL | In Vivo Grade | 3~4 weeks |
SL100862 | rAAV Packaging Service, Large Scale | 1.0 mL at >1E+13 VG/mL | In Vivo Grade | 1~2 weeks |
SL100863 | rAAV Packaging Service, Medium Scale | 0.2 mL at >1E+13 VG/mL | In Vivo Grade | 1~2 weeks |
SL100864 | rAAV Packaging Service, Pilot Scale | 0.1 mL at >1E+13 VG/mL | In Vivo Grade | 1~2 weeks |
Large AAV cis vector collection offers tremendous flexibility for choosing a specific promoter and reporter.
Single promoter rAAV cis vector | Dual promoter rAAV cis vector | |||
Promoterless CMV CAG H1 U6 Synapsin UBC EF1α ALB(1.4) ApoE/AAT1 CaMKII ELA1 Enh358MCK cTNT GFAP MBP SST TBG αMHC hRPE mIP1 tMCK |
Promoterless CMV CAG H1 U6 Synapsin UBC EF1α ALB(1.4) ApoE/AAT1 CaMKII ELA1 Enh358MCK cTNT GFAP MBP SST TBG αMHC hRPE mIP1 tMCK |
CMV CAG H1 U6 Synapsin UBC EF1α CaMKII cTNT GFAP |
eGFP RFP mRFP mCherry tdTOMATO TurboGFP eYFP Venus Luc LacZ |
With our proprietary genetically engineered AAV·HT™ packaging cell and a modified rAAV cis vector, the rAAV yield is easy to reach super high level——–total 1E+15 VG. For super high level rAAV production up to 1E+15 VG total , please contact us to request a quote.
* Final viral yield may depend on the nature of transgene.
** Some terms may apply for custom double stranded or self-complementary rAAV production.
To learn more, please visit http://signagen.com/AAV-Production-Service