Skip to content

Adeno-associated Virus (AAV) - 19. page

>400 Pre-made Ready to Use rAAVs from SignaGen

All the following pre-made AAVs were packaged in serotype 1**, 2, 5, 6, 8** and 9** and super purified via 2xCsCl ultra-centrifugation in in-vivo grade.  All the pre-packaged rAAVs were […]

Summary of clinical trials using AAV gene transfer

Disease Transgene product Serotype Route of administration Clinical trial ClinicalTrials.gov identifier Refs AAV clinical trials for inherited diseases α1 antitrypsin deficiency α1 antitrypsin AAV2 Intramuscular Phase I/II NCT00377416 101,102 AAV1 […]

Key properties of a viral vector

Viral vectors are tailored to their specific applications but generally share a few key properties: Safety: Although viral vectors are occasionally created from pathogenic viruses, they are modified in such […]

rAAV Vector Tropism

rAAV Vector Tropism: rAAV Serotype Applications (X = Recommended for use) Skeletal muscle Heart Lung CNS / Eye Liver Adipose AAV1 X X X X – – AAV2 – – […]

GCaMP6 calcium indicators

Name Description Addgene Plasmid ID Reference CMV-GCaMP6s improved SNR, slower kinetics 40753 Chen et al., 2013 CMV-GCaMP6m improved SNR, intermediate kinetics 40754 Chen et al., 2013 CMV-GCaMP6f improved SNR, faster […]

Cre-inducible Adeno-associated Virus: DIO-AAV

For cell type-specific targeting and to capitalize on the large number of Cre driver lines with the flexible virus injection/fiberoptic approach, we have developed a tool we call DIO-AAV (doublefloxed […]

SignaGen’s rAAV Production Service

Multi Approaches to Produce Super Infectious rAAV Particles at Super High Titer: Not like adenovirus, it is relatively harder to achieve high yield of rAAV with regular rAAV production procedures. […]