AAV-TRAC-HRv2-P2A1928z-P2A41BBL Ready to Package
Adeno-associated Virus (AAV) - 12. page
Gene Editing of CD+8 and CD+4 T Cell Genome via rAAV Transduction in Serotype 6
Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery The adoptive transfer of engineered T cells for the treatment of cancer, autoimmunity, and infectious disease […]
AAV9-GFAP-GFP Ready to Package
AAV9-GFAP-GFP Ready to Package
An Ancestral rAAV Serotype Anc80L65
The researchers synthesized one of the ancestral AAVs, Anc80L65, and showed that it could infect mouse liver, muscle and retina, without eliciting a major immune response. In addition, Anc80L65 was […]
AAV8-ApoE/AAT1-Luc Ready to Package
AAV8-ApoE/AAT1-Luc Ready to Package
A Novel AAV Capsid AAV-AS Was Recently Identified
A novel vector AAV-AS, generated by the insertion of a poly-alanine peptide, is capable of extensive gene transfer throughout the CNS after systemic administration in adult mice. AAV-AS is 6- […]
AAV-CaMKIIa-hM4D(Gi)-mCherry Ready to Package
AAV-CaMKIIa-hM4D(Gi)-mCherry Ready to Package
AAV Serotype PHP.B2 VP1 Sequence
atggctgccgatggttatcttccagattggctcgaggacaaccttagtgaaggaattcgcgagtggtgggctttgaaacctggagcccctcaacccaaggcaa atcaacaacatcaagacaacgctcgaggtcttgtgcttccgggttacaaataccttggacccggcaacggactcgacaagggggagccggtcaacgcagcagacgc ggcggccctcgagcacgacaaggcctacgaccagcagctcaaggccggagacaacccgtacctcaagtacaaccacgccgacgccgagttccaggagcggctcaaaga agatacgtcttttgggggcaacctcgggcgagcagtcttccaggccaaaaagaggcttcttgaacctcttggtctggttgaggaagcggctaagacggctcctgga aagaagaggcctgtagagcagtctcctcaggaaccggactcctccgcgggtattggcaaatcgggtgcacagcccgctaaaaagagactcaatttcggtcagact ggcgacacagagtcagtcccagaccctcaaccaatcggagaacctcccgcagccccctcaggtgtgggatctcttacaatggcttcaggtggtggcgcaccagtgg cagacaataacgaaggtgccgatggagtgggtagttcctcgggaaattggcattgcgattcccaatggctgggggacagagtcatcaccaccagcacccgaacc tgggccctgcccacctacaacaatcacctctacaagcaaatctccaacagcacatctggaggatcttcaaatgacaacgcctacttcggctacagcaccccctgggg gtattttgacttcaacagattccactgccacttctcaccacgtgactggcagcgactcatcaacaacaactggggattccggcctaagcgactcaacttcaagctctt caacattcaggtcaaagaggttacggacaacaatggagtcaagaccatcgccaataaccttaccagcacggtccaggtcttcacggactcagactatcagctccc gtacgtgctcgggtcggctcacgagggctgcctcccgccgttcccagcggacgttttcatgattcctcagtacgggtatctgacgcttaatgatggaagccaggcc gtgggtcgttcgtccttttactgcctggaatatttcccgtcgcaaatgctaagaacgggtaacaacttccagttcagctacgagtttgagaacgtacctttccatag cagctacgctcacagccaaagcctggaccgactaatgaatccactcatcgaccaatacttgtactatctctctagaactattaacggttctggacagaatcaacaaa cgctaaaattcagtgtggccggacccagcaacatggctgtccagggaagaaactacatacctggacccagctaccgacaacaacgtgtctcaaccactgtgactca aaacaacaacagcgaatttgcttggcctggagcttcttcttgggctctcaatggacgtaatagcttgatgaatcctggacctgctatggccagccacaaagaagga gaggaccgtttctttcctttgtctggatctttaatttttggcaaacaaggtaccggcagagacaacgtggatgcggacaaagtcatgataaccaacgaagaagaa attaaaactactaacccggtagcaacggagtcctatggacaagtggccacaaaccaccagagtgcccaaagtgtgagtaagccttttttggcacaggcgcagacc ggttgggttcaaaaccaaggaatacttccgggtatggtttggcaggacagagatgtgtacctgcaaggacccatttgggccaaaattcctcacacggacggcaa ctttcacccttctccgctgatgggagggtttggaatgaagcacccgcctcctcagatcctcatcaaaaacacacctgtacctgcggatcctccaacggccttcaacaa ggacaagctgaactctttcatcacccagtattctactggccaagtcagcgtggagatcgagtgggagctgcagaaggaaaacagcaagcgctggaacccggaga tccagtacacttccaactattacaagtctaataatgttgaatttgctgttaatactgaaggtgtatatagtgaaccccgccccattggcaccagatacctgactcgtaatctgtaa
AAV Serotype PHP.B VP1 Sequence
AAV-PHP.B is a capsid variant derived from AAV serotype 9 that additionally contains the heptapeptide TLAVPFK. This AAV variant can cross the blood-brain barrier after intravenous injection and was selected […]
Novel AAV Serotypes to Penetrate Blood-brain Barrier for Full Transgene Expression in CNS
Recombinant adeno-associated viruses (rAAVs) are commonly used vehicles for in vivo gene transfer. However, the tropism repertoire of naturally occurring AAVs is limited, prompting a search for novel AAV capsids […]