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Miscellaneous - 15. page

First Success With CAR T-Cells in a Solid Tumor

Chimeric antigen-receptor (CAR) T-cell therapy has repeatedly provided dramatic results in patients with hematologic malignancies. Now comes the first success story of CAR T-cell therapy in a solid tumor — […]

Eukaryotic Promoter Database

EPDnew (Eukaryotic Promoter Database) – is a new collection of experimentally validated promoters in human, mouse, D. melanogaster and zebrafish genomes.  Evidence comes from TSS-mapping from high-throughput expreriments such as […]

Common promoters for eukaryotes and prokaryotes

Eukaryotic Promoters   Promoter Primarily used for RNA     transcript Description Expression Additional considerations CMV General expression mRNA Stong mammalian expression promoter from the human cytomegalovirus Constitutive May contain an enhancer region. […]

DMTMM A Novel Coupling Reagent

Propylphosphonic anhydride (T3P®) is a very efficient, nontoxic coupling reagent especially suited for connecting sterically hindered amino acids. A further advantage is the easy removal of byproducts by extraction of the […]

Applications of Channelrhodopsin

Channelrhodopsins can be readily expressed in excitable cells such as neurons using a variety of transfection techniques (viral transfection, electroporation, gene gun). The light-absorbing pigment retinal is present in most […]

Discovery of Channelrhodopsin

Motility and photoorientation of microalgae have been studied over more than hundred years in many laboratories worldwide. In 1980, Ken Foster developed the first consistent theory about the functionality of […]

Predesigned/Validated siRNA

Instructions: Please select a siRNA database from the pull down menu. At present we offer control duplexes and pre-designed siRNAs for over 17,000 reviewed genes based on the NCBI Refseq […]