Miscellaneous - 9. page

CTTCCAATTTACTCTGAGAA

MYH9: MYH9-5   GUAUCAAUGUGACCGAUUU    Good + MHH9-6  CAAAGGAGCCCUGGCGUUA     Good + MYH9-7   GGAGGAACGCCGAGCAGUA     Good ++ MYH9-8   CGAAGCGGGUGAAAGCAAA    Good + MYH9-9   GGGUAUCAAUGUGACCGAUUU   Good + MYH9-10 CGGCAAGGUGGAUUACAAAUU   Good ++ MYH10: […]

The following siRNA sequences were efficacious in knocking down dystonin-a1 and dystonin-a2 expression, respectively: Group A: Sense: 5’-ACAUGUACGUGGAGGAGCA-3’ / Antisense: 5’-UGCUCCUCCACGUACAUGU-3’; Sense: 5’-CAAGCAUGAGAGAUCCAAA-3’ / Antisense: 5’-UUUGGAUCUCUCAUGCUUG-3’; Group B: Sense: 5’-CAAGCAUGAGAGAUCCAAA-3’ […]

Validated mouse dystonin shRNA: CCGGCCCTTGTCAAACTCTACGAAACTCGAGTTTCGTAGAGTTTGACAAGGGTTTTTG

UUGCACAGCAGCCGGUUUAUU

mPDK4 Validated siRNA CCGUCUCUACGCCAAGUAUTT

COX-2 siRNA: 5-AACTGCTCAACACCGGAATTTTT-3 COX-1 siRNA: 5-AAGTGCCATCCAAACTCTATCTT-3 15-PGDH siRNA: 5-AACAGTGGTGTGAGACTGAAT-3

15-PGDH and Scramble control siRNA sequence: 15-PGDH: (NM_001034419.2) 5′-GCUUUGAA UGGUGCUAUUATT-3′ Scramble: 5′-UUCUCCGAACGUGUCAC GUTT-3′ HIF-1α siRNA: (NM_174339.3) 5′-GCUCCUGAGGAAGAACUAATT-3′ Scramble: 5′-UUCUCCG AACGUGUCACGUTT-3′

15PGDH-specific shRNAs target region sequence: 1) CACAGCCATCCTTGAATCAAT 2) GAAGGCGGCATCATTATCAAT 3) GCAACAACTGAGAGACACTTT 4) CTGGAGTGAATAATGAGAAA 5) ACTCATAACAACACAGACATA

Mouse FOXO3 siRNA: 5′-CCAGUGACUUGGACCUGGACAUGUU-3′