rShH10 expression following intravitreal injection in the adult rat retina. Confocal imaging of immunostained transverse retinal sections 3 weeks post-injection of 2.5×1010 viral particles (vector genomes) of dsCAG-GFP vectors with […]
DNA Shuffling of Adeno-associated Virus Yields Functionally Diverse Viral Progeny
Adeno-associated virus (AAV) vectors are extremely effective gene-delivery vehicles for a broad range of applications. However, the therapeutic efficacy of these and other vectors is currently limited by barriers to […]
Universal Primers
Standard primer name Sequence (5′->3′) Number of bases 1629DWN CTG TAA ATC AAC AAC GCA CAG 21 3AOX1 <GCA AAT GGC ATT CTG ACA TCC 21 5AOX1 < GAC TGG […]
Universal Primer List
PRIMERS SEQUENCES 3’ AD 5’ (AGA TGG TGC ACG ATG CAC AG) 3’ 3 AOX1 5′ (GCA AAT GGC ATT CTG ACA TCC) 3’ 5’ AD 5’ (TTC GAT […]
miRNA Database
http://www.mirbase.org/index.shtml
Multiple Sequence Alignment
http://www.ebi.ac.uk/Tools/msa/
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures
Table 1. Comparison table of optogenetic tools suitable for fast in vivo use in mammals and other animals. Next table | Figures & tables Opsin Host organism Wavelength sensitivity Mode […]
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
Exosomes and microvesicles are extracellular nanovesicles released by most but not all cells. They are specifically equipped to mediate intercellular communication via the transfer of genetic information, including the transfer […]
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
Despite the therapeutic potential of nucleic acid drugs, their clinical application has been limited in part by a lack of appropriate delivery systems. Exosomes or microvesicles are small endosomally derived […]
Exosome
Exosomes are cell-derived vesicles that are present in many and perhaps all biological fluids, including blood, urine, and cultured medium of cell cultures. The reported diameter of exosomes is between […]