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Comprehensive AAV Production Services
Scalable rAAV production solutions encompassing vector design, optional gene synthesis, AAV packaging, purification, and quality control…
From Concept to Delivery: Our Workflow
A streamlined process that delivers speed without compromising scientific rigor
AAV Vector Design & Gene Synthesis
Software-assisted AAV cis vector design for overexpression of transgene, shRNA, shRNAmir, miRNA, gRNA, or TuD RNA
WEEK 1
AAV cis Construct Cloning & Verification
GAC or RE cloning followed by verification via restriction digestion & WPS of NanoPore
WEEK 2
AAV Packaging & Harvest
Helper-free triple transfection in HEK293T cells, followed by AAV harvest
WEEK 3
AAV Purification & Quality Control
AAV purification via ultracentrifugation, followed by qPCR Titration & Other QCs
WEEK 4
Why SignaGen?
Reasons customers trust us for AAV production services
Extensive Promoter & Serotype Options
Constitutively active or tissue-specific gene expression enabled by our extensive promoter and AAV capsid library
1,500+ empty AAV cis vectors with diverse promoters, introns, WPREs, and polyA signals
160+ naturally occurring & engineered / synthetic AAV capsid viral plasmids
Custom promoter & AAV capsid synthesis & validation when off-the-shelf options are unavailable
AAV designs and related IP belong to the customer, who receives the final AAV vector and cloned cis construct
Rigorous Quality Validation
Technical Benchmarks
We Offer Fully Customizable AAV Production Services
| SKU # | SERVICES | FINAL DELIVERABLE | PURITY | TURNAROUND TIME |
|---|---|---|---|---|
| SL100865 | AAV PRODUCTION FULL SERVICE, PILOT SCALE | 100 µL at >10¹³ VG/mL | In vivo grade | 4 weeks |
| SL100861 | AAV PRODUCTION FULL SERVICE, MEDIUM SCALE | 200 µL at >10¹³ VG/mL | In vivo grade | 4 weeks |
| SL100801 | AAV PRODUCTION FULL SERVICE, LARGE SCALE | 1000 µL at >10¹³ VG/mL | In vivo grade | 4 weeks |
| SL100801-MS | AAV PRODUCTION FULL SERVICE, MEGA SCALE | 10 mL at >10¹³ VG/mL | In vivo grade | 4 weeks |
| SL100801-GS | AAV PRODUCTION FULL SERVICE, GIGA SCALE | 100 mL at >10¹³ VG/mL | In vivo grade | 6 weeks |
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We price-match competitors & provide an additional 10% discount
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