Feature	Details
Origin	Isolated from the lymph nodes of Rhesus Macaques.
Primary Receptor	AAVR (KIAA0319L) — required for entry.
Co-receptors	N-linked Sialic Acid (a-2,3 and a-2,6).
Primary Tropism	Skeletal Muscle, Heart (Myocardium), Liver.
Secondary Tropism	Diaphragm and Vascular Smooth Muscle.
Clinical Fame	Vector for Elevidys (First FDA-approved DMD gene therapy).
Unique Trait	Extreme Myotropism: Highly efficient at transducing muscle fibers throughout the body.
Seroprevalence	Very Low in Humans (~14% to 17% have pre-existing antibodies).
Similarity	Shares ~93% amino acid identity with AAV8.