Feature	Details
Origin	Isolated from human tissue (human liver/heart DNA).
Primary Receptor	Terminal N-linked Galactose (Unique to AAV9).
Co-receptors	AAVR (KIAA0319L) and possibly LamR.
Primary Tropism	CNS (Neurons & Astrocytes), Heart, Liver, Skeletal Muscle.
Clinical Fame	Vector for Zolgensma (FDA-approved for Spinal Muscular Atrophy).
BBB Capability	High — Can cross the adult and neonatal blood-brain barrier.
Seroprevalence	Relatively Low (~20% to 30% of humans have antibodies).
Unique Trait	Switches preference from Neurons (neonates) to Astrocytes (adults).