Feature	Details
Origin	Isolated from African Green Monkeys (Simian origin).
Primary Receptor	α–2,3 O-linked Sialic Acid (Mucins).
AAVR Usage	Independent (Unique because most AAVs require AAVR to infect).
Primary Tropism	Ependymal cells (CNS), Retinal Pigment Epithelium (RPE).
Secondary Tropism	Heart, Lung, and Pancreatic Beta cells (in some models).
Clinical/Research Focus	Hydrocephalus, Neurological secretory diseases, and Blindness.
Unique Trait	Antigenically distant (Few humans have pre-existing immunity).
Structural Profile	Most divergent capsid surface compared to AAV2 (~58% homology).