Feature	Details
Origin	Isolated from human/non-human primate tissue (Clade C).
Primary Receptor	HSPG (Heparan Sulfate Proteoglycan) — similar to AAV2.
Co-receptors	AAVR (KIAA0319L) — the universal AAV entry factor.
Primary Tropism	CNS (Neurons), Liver, and some Muscle.
Unique Trait	Confined Diffusion: Does not spread far from the injection site.
Transport Mode	Anterograde-only: Travels from the cell body to the axon tip.
Research Fame	Used for “Sparse Labeling” (mapping individual neurons).
Production	Highly efficient; often yields higher titers than AAV2 in the lab.