AAV-TTR-Cre (AAV Serotype 8)

Product Category: Pre-made recombinant AAV | AAV-TTR-Cre | AAV8-TTR-Cre
Description:
AAV8-TTR-Cre is a pre-packaged recombinant AAV serotype 8 vector (AAV8 capsid with AAV2 ITRs) that expresses Cre recombinase under the control of the liver-specific transthyretin (TTR) promoter. This design enables robust, hepatocyte-targeted Cre expression for efficient recombination of floxed (LoxP-flanked) alleles in liver tissue. Cre recombinase, derived from bacteriophage P1, catalyzes site-specific recombination between LoxP sites and is widely used for conditional gene knockout or activation in cells and experimental animals. Supplied in a ready-to-use format for in vitro and in vivo applications.
Titer: >1E+13 VG/mL
Size: 30 µL (Std Pack)
Reconstitution Buffer: Sterile PBS supplemented with final 0.005% Pluronic F-68 and 200 mM NaCl
CITATIONS
| Shipping Weight | 6 lbs |
|---|---|
| Unit Size | 30 µL at >10¹³ VG/mL, 10 µL at >10¹³ VG/mL |
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