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AAV-TBG-Cre (AAV Serotype 8)
Product Category: Pre-made recombinant AAV; AAV-TBG-Cre; AAV8-TBG-Cre; AAV-TBG-Intron-Cre; AAV8-TBG-Intron-Cre
Description:
AAV8-TBG-Cre is a pre-packaged recombinant AAV (rAAV) vector in serotype 8 (AAV8 capsid with 2× ITRs derived from AAV serotype 2) that expresses Cre recombinase under the control of the liver-specific TBG promoter. The TBG promoter is a hybrid promoter based on the human thyroxine-binding globulin (TBG) promoter and the α1-microglobulin/bikunin enhancer. Approximately 0.8 kb in length, the TBG promoter is widely used to drive robust and liver-specific transgene expression. AAV8-TBG-Cre is particularly suitable for Cre-mediated recombination in hepatocytes and can be used for liver-specific gene knockout, gene activation, lineage tracing, and other Cre/loxP-based studies in vivo.
Titer: >1E+13 VG/mL
Size: 30 µL (Std Pack)
Reconstitution Buffer: Sterile PBS supplemented with final 0.005% Pluronic F-68 and 200 mM NaCl
Infection Protocol: 
Vector Map:
CITATIONS
| Shipping Weight | 6 lbs |
|---|---|
| Unit Size | 100 (2 x 50) µL at >10¹³ VG/mL, 50 µL at >10¹³ VG/mL |
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