AAV-Syn-Cre (AAV Serotype PHP.eB)

Product Category: Pre-made recombinant AAV; AAV-Synapsin-Cre; AAV(PHP.eB)-Synapsin-Cre; AAV-Syn-Cre; AAV(PHP.eB)-Syn-Cre
Description: AAV(PHP.eB)-Synapsin-Cre is a pre-packaged rAAV in serotype PHP.eB (with capsid from AAV serotype PHP.eB and 2xITR from AAV serotype 2) which over-expresses Cre recombinase under human synapsin promoter for exclusive neuronal expression. This product used in the Cre-lox system as a genetic tool to generate site-specific recombination of DNA between loxP sites in cultured cells and animal experiments. Compared with rAAV serotype PHP.B, rAAV in serotype PHP.eB is able to penetrate brain-blood barrier (BBB) and infect CNS via tail vein I.V. with 5 times better transduction efficiency. Ready to use format.
Titer: >1E+13 VG/mL
Size: >30 µL(Std Pack)
Reconstitution Buffer: Sterile PBS supplemented with final 0.005% Pluronic F-68 and 200 mM NaCl
CITATIONS
| Shipping Weight | 6 lbs |
|---|---|
| Unit Size | 30 µL at >10¹³ VG/mL, 10 µL at >10¹³ VG/mL |
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