Monthly Archives: May 2025
Deletion of the B-B’ or C-C’ in AAV ITR has a minimal impact on AAV production but increases transgene expression
1. ITR Structure and Function• ITRs are crucial: ITRs are key elements in AAV vectors, serving as origins of replication, and are essential for viral genome replication, packaging into capsids, […]
How Does pH Affect DNA Stability?
In a neutral pH range, pH 5 to 9, DNA molecules are quite stable. However, if the pH becomes too acidic or alkaline, DNA molecules are prone to destabilization. At […]