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Miscellaneous - 14. page

Codon Adaptation Index

The Codon Adaptation Index (CAI) is the most widespread technique for analyzing Codon usage bias. As opposed to other measures of codon usage bias, such as the ‘effective number of […]

Codon usage bias

Codon usage bias refers to differences in the frequency of occurrence of synonymous codons in coding DNA. A codon is a series of three nucleotides (a triplet) that encodes a […]

First Success With CAR T-Cells in a Solid Tumor

Chimeric antigen-receptor (CAR) T-cell therapy has repeatedly provided dramatic results in patients with hematologic malignancies. Now comes the first success story of CAR T-cell therapy in a solid tumor — […]

Eukaryotic Promoter Database

EPDnew (Eukaryotic Promoter Database) – is a new collection of experimentally validated promoters in human, mouse, D. melanogaster and zebrafish genomes.  Evidence comes from TSS-mapping from high-throughput expreriments such as […]

Common promoters for eukaryotes and prokaryotes

Eukaryotic Promoters   Promoter Primarily used for RNA     transcript Description Expression Additional considerations CMV General expression mRNA Stong mammalian expression promoter from the human cytomegalovirus Constitutive May contain an enhancer region. […]

DMTMM A Novel Coupling Reagent

Propylphosphonic anhydride (T3P®) is a very efficient, nontoxic coupling reagent especially suited for connecting sterically hindered amino acids. A further advantage is the easy removal of byproducts by extraction of the […]