AAV-CAG-FLPo (AAV Serotype 6)

Price: $488.00

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  • Catalog #: SL101454
  • Unit Size: 1 x >30 µL (>1E+13 VG/mL)

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Pre-made recombinant AAV; AAV-CAG-FLPo; AAV-CBA-FLPo; AAV6-CAG-FLPo; AAV6-CBA-FLPo

Product Category: Pre-made recombinant AAV; AAV-CAG-FLPo; AAV-CBA-FLPo; AAV6-CAG-FLPo; AAV6-CBA-FLPo

Description: FLP originally identified from Saccharomyces cerevisiae is a site-specific recombinases (SSR) from the φ integrase family and recognizes distinct 34 bp FRT sequence. It has been widely used for generating conditional knockout mice, mediated by FLP/FRT system. Initial use of FLP in mammalian cells revealed inefficient recombinase activity due to thermo-instability of the FLP protein. Subsequent screening for thermo-stable mutants resulted in the identification of FLPe which was 4-fold increase in recombination efficiency at 37 °C. However the recombination efficiency of FLPe in cells remains very low because of its non-mammalian origin.  

FLPo is a mouse codon optimized FLPe that greatly increases the FRT recombination efficiency for both in vivo and in vitro in mouse. 
This AAV6
-CAG-FLPo pre-made rAAV in serotype 6 (with capsid from AAV serotype 6 and 2xITR from AAV serotype 2) will over-express FLPo recombinase under CAG promoter (also known as CBA promoter).  Ready to use format.

Titer: > 1x10^13 VG/mL

Size: > 30 µL (Std Pack)

Storage Buffer: Sterile PBS

Infection Protocol: 

Vector Map: 

Pre-made recombinant AAV; AAV-CAG-FLPo; AAV-CBA-FLPo; AAV6-CAG-FLPo; AAV6-CBA-FLPo




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